This trial will assess the efficacy and safety of AXS-05, an investigational drug combining FDA-approved bupropion and dextromethorphan, to treat agitation in older adults with Alzheimer’s disease.
Researchers are exploring this treatment for Alzheimer’s-related agitation, characterized by emotional distress, aggressive behaviors, disruptive irritability, and disinhibition. This study will compare the effectiveness of AXS-05 to that of bupropion alone or a placebo. Participants will take a pill of either the study drug or a placebo once daily by mouth for 5 weeks.
Find out whether you or your loved one is eligible for the trial.