March 28, 2024

Study confirms menopause transition increases risk of Alzheimer’s

Lisa Mosconi of Weill Cornell Medical College in collaboration with Roberta Diaz Brinton at the Departments of Pharmacology and Neurology, College of Medicine, University of Arizona, Tucson, conducted a three-year longitudinal brain imaging study.

It was supported by Cure Alzheimer’s Fund.

Details of the study

The participants of the study were asked to undergo tests to assess cognitive performance as well as imaging to assess brain b-amyloid load.

The participants included both men and women.

The female participants included women, who were either premenopausal, perimenopausal, or postmenopausal. The study found that in the menopausal and perimenopausal group there was a decline in an estrogen-dependent memory test as compared to men.

Result of the study

The menopausal group exhibited the highest rate of loss in an area of the brain critical for memory known as the hippocampus as well as the greatest increase in Ab deposition.

Find the full report of the study here and also get to know why women are at increased risk for developing Alzheimer’s.

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